Disruptive drugs against
Neuropathic pain

An estimated 10% of the western population suffers from chronic neuropathic pain. Current drugs are hampered by limited effectiveness and central nervous system side effects.

AKIGAI’s mission
is clear and stedfast.

“To make an EGFR-inhibitor available to as many neuropathic pain patients as possible, as quickly as possible.”

To this end, we have mapped all marketed EGFR-inhibitors and >60 development candidates that have been tested in clinical trials.

After in-silico research, experiments in rodent models, as well as years of observations in 100+ successfully treated neuropathic pain patients with 11 different pain entities, one of the EGFR-inhibitors approved for the treatment of cancer stands out.

The EGFR ReceptorThe EGFR Receptor

The EGFR is one of the most studied molecules in the human body.

The science behind AKIGAI's approach

The Two Routes of Administration

AKIGAI's approach is twofold. We envision two paths to development of a new type of EGFR-inhibitor.

Learn about our approach
1. Tyrosine kinase inhibitors given as tablets 2. Monoclonal antibodies for parenteral use

Latest news from AKIGAI

AKIGAI founders featured in Mighty Spark Communications Podcast

AKIGAI Welcomes Strategic Investment Partner!

AKIGAI has secured a strategic partnership with investor Brynjar Forbergskog

FDA grants Orphan Designation for the treatment of CRPS with AKI-007

Dramatic, durable and safe pain relief in chronic CRPS patients has lead to this milestone. A phase III trial is the next step.

Collaborate with AKIGAI

AKIGAI is looking for partners and collaborators to help realize EGFR-inhibitors for use against neuropathic pain.

More about collaborations

We are proud to be
working with

Startuplab
Sørlandet Sykehus

Møsbu AS